Delivering results. Confidently.
Expectant couples are often overwhelmed with information. They’re anxious. They’re worried. And they’re looking to you for answers. The MaterniT21™ PLUS laboratory-developed test provides you and your patients with highly accurate results so you and your patients can have important information.
The MaterniT21 PLUS test is a noninvasive prenatal test that detects fetal chromosomal abnormalities; from common (trisomies 21, 18 and 13) to the more rare (fetal sex aneuploidies, trisomies 16 and 22, and select microdeletions), all of the information reported is clinically relevant.
MaterniT21 PLUS sets the benchmark for noninvasive prenatal testing.
The MaterniT21 PLUS test is designed to capitalize on its powerful technological capabilities. Using versatile technology, the MaterniT21 PLUS test brings information to you and your patients in an unprecedented noninvasive prenatal test.
THE ENHANCED SEQUENCING SERIES, EXCLUSIVELY FOR THE MATERNIT21 PLUS TEST
Meaningful answers. Clear results. The power of MPS.
Massively parallel sequencing (MPS) is uniquely positioned to realize the promise of delivering relevant, enhanced information. Other methods lack the adaptability to efficiently add meaningful content.
The MaterniT21 PLUS test delivers revolutionary content. This is merely a glimpse of all that it will offer you and your patients over time. You can count on the MaterniT21 PLUS test to provide you with clarity, allowing you to provide the most advanced information available to your patients, noninvasively.
INNOVATION TRANSLATING TO PREMIUM CONTENT
In addition to content that you have come to rely on (chromosomes 21, 18, 13, X and fetal gender), the Enhanced Sequencing Series includes:
- 22q deletion syndrome (DiGeorge)
- 5p (Cri-du-chat syndrome)
- 15q (Prader-Willi/Angelman syndromes)
- 1p36 deletion syndrome
- 4p (Wolf-Hirschhorn syndrome)
- 8q (Langer-Giedion syndrome)
- 11q (Jacobsen syndrome)
- Trisomy 16
- Trisomy 22
There’s no room for maybe.
Other prenatal tests offer risk scores or unclear results. The MaterniT21 PLUS test reports test results as positive, negative or an Additional Finding, providing you and your patients with clear results.
Palomaki9,10, Bianchi13, Norton14, Zimmermann17.
Get an answer. The first time.
The MaterniT21 PLUS test has the lowest published and commercial non-reportable results rates to date. The unmatched performance of the MaterniT21 PLUS test means your patients can avoid retesting or potentially an unnecessary invasive procedure due to non-reportable results rates.
Clinical indications for testing.
We offer this test for pregnancies with one or more of the following conditions:
- Advanced maternal age
- Personal or family history of chromosomal abnormalities
- Fetal ultrasound abnormality suggestive of chromosomal abnormalities
- Positive serum screening test
About the test.
What does it test for?
The MaterniT21 PLUS laboratory-developed test for chromosomal abnormalities. The MaterniT21 PLUS tests for fetal chromosomal abnormalities for trisomy 21, 18 and 13. In addition, when a clear result is seen, our laboratory will also report fetal sex aneuploidies, trisomy 16 and 22, and select microdeletions, including 22q (DiGeorge syndrome), 15q (Prader-Willi/Angelman syndromes), 11q (Jacobsen syndrome), 8q (Langer-Giedion syndrome), 5p (Cri-du-chat syndrome), 4p (Wolf-Hirschhorn syndrome), and 1p36 deletion syndrome as an Additional Finding.
What specific fetal sex aneuploidies does it look for?
X, XXX, XYY, XXY
When can it be used?
Our test is indicated for use as early as 10 weeks’ gestation.
What specific information is included with the Enhanced Sequencing Series?
22q (DiGeorge syndrome), 15q (Prader-Willi/Angelman syndromes), 11q (Jacobsen syndrome), 8q (Langer-Giedion syndrome), 5p (Cri-du-chat syndrome), 4p (Wolf-Hirschhorn syndrome), 1p36 deletion syndrome, trisomy 16, and trisomy 22.
What is the turnaround time?
The blood sample is sent to the laboratory and results are reported to you in approximately 5 days from receipt of the sample in the lab.
How many tubes of blood do you need to run test?
2 x 10 mL in the mottled black/tan top blood collection tubes that are provided.
Are there any clinical restrictions that I should know about your test?
We can run samples from multifetal gestations in this pregnancy, egg donors, and IVF patients -- essentially any increased risk pregnant woman.
How well does it work?
The MaterniT21 PLUS test sensitivity ranges from 99.1% for trisomy 21; > 99.9% for trisomy 18; and 91.7% for trisomy 13, while maintaining a very low false positive rate (95% CI - 96.3–99.8%; 92.4-100%; and 59.7-99.6% respectively).
Prenatal provider materials.
Do you want to learn more about the MaterniT21 PLUS laboratory-developed test, as well as the other tests in our prenatal portfolio? Click on any of these images below to view and/or download them digitally.
Prenatal webinars for providers
22q and You: Implementing the MaterniT21 PLUS
Enhanced Sequencing Series into your practice