|We’re proud to feature MaterniT21TM PLUS
now on the Ovia Pregnancy app. We’ve partnered with Ovia to help you track your pregnancy while providing tailored first and second trimester testing information that
matters most to you. It’s free and available
now! Download the app: iTunes | Web version
It’s your pregnancy. Demand the accuracy of the MaterniT21TM PLUS Test.
To date, our MaterniT21 PLUS laboratory-developed test is the most technologically advanced noninvasive prenatal test of its kind on the market for detecting fetal chromosomal abnormalities. With industry-leading clinical performance, you can be confident in the results. The test is noninvasive, requiring only a blood sample. And it can be performed as early as ten weeks’ gestation with results provided to your health care provider about seven business days from receipt of your sample in our laboratory.
No confusion. Just simple, clear results.
The MaterniT21 PLUS test offers a powerful glimpse into the pregnancy by evaluating relative amounts of chromosomal material. Analysis of chromosomes 21, 18, 13, X and Y, occur with every test.
The MaterniT21 PLUS test reports simple positive or negative results. This gives you and your health care provider the clarity and confidence you need to plan effectively. Please discuss all your prenatal testing options with your health care provider.
Even more answers are now available.
Your health care provider can also choose to request even more chromosomal information be evaluated. Chromosomes 22, 16, and select chromosomal regions including 22q, 15q, 5p and 1p are now available for analysis. This represents the most comprehensive information available from any noninvasive prenatal test.
Changes to these particular chromosomes are quite rare. In the infrequent occurrence where a risk was identified, results are reported as an Additional Finding. Absence of an Additional Finding does not indicate a negative result.
The American College of Obstetricians and Gynecologists (ACOG) recommends that all pregnant women be offered a screening test for fetal chromosomal abnormalities, regardless of the woman’s age1. Testing may include:
- A maternal blood test done in the first trimester along with ultrasound.
- A maternal blood test done in the second trimester without ultrasound.
- A combination of both1.
ACOG also recommends that invasive diagnostic testing such as chorionic villus sampling (CVS) or genetic amniocentesis for chromosome abnormalities should be made available to all women, regardless of age2. These procedures obtain tissue/cells that allow for highly accurate diagnosis of genetic variations like trisomy 21, 18 or 13. Both CVS and amniocentesis are invasive procedures and carry a small risk of causing a miscarriage.
In 2012, ACOG and the Society for Maternal-Fetal Medicine (SMFM) issued a joint committee opinion that supported noninvasive prenatal testing that uses cell-free fetal DNA for women at increased risk for having a baby with a chromosomal abnormality3. ACOG also recommended that all women considering this testing have genetic counseling to better understand their options.
About chromosomal abnormalities.
Chromosomes are structures inside every cell of your body. They hold the genes, inherited from your mother and father, that tell your body how to grow and develop. Most people have 23 pairs of chromosomes, each carrying thousands of genes. The first 22 pairs are called the autosomes, and are identical in males and females. The 23rd pair is the sex chromosomes–X and Y. Females usually have two X chromosomes, males have one X chromosome and one Y chromosome. Some people are born with an extra or missing chromosome, meaning they have three copies of a chromosome instead of two. This is known as a trisomy. The most common fetal trisomies are trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome).
Beyond whole chromosome changes.
Some chromosome changes (see 22q11.2 deletion syndrome, Cri-du-Chat syndrome, Prader-Willi/Angelman syndrome, and 1p36 below) that happen don’t involve whole chromosomes, but small pieces of chromosome material instead. These types of changes can cause specific traits or characteristics to occur. These conditions are very rare. They can be diagnosed using a procedure called CVS or amniocentesis if there is a suspicion following other prenatal testing. Discussing with your health care provider the risk of having a baby with one of these conditions is encouraged if testing identifies a risk.
Simple answers to important questions.