Cystic fibrosis is one of the most common genetic conditions in the United States. Changes in the CFTR gene cause the body to produce thick sticky mucus in the lungs, pancreas and other organs that can affect breathing and digestion. CF does not affect everyone the same way - some people may be more severely affected than others. Symptoms can range from moderate to severe and can even impact fertility. The average lifespan of someone with CF is 37 years33.
It is estimated that more than 10 million Americans are carriers of CF. While the risk of being a CF carrier is dependent upon one's ethnicity and family history, individuals of all racial and ethnic groups may be carriers.
For more information, please visit the Johns Hopkins CFTR2 website.